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Who we are

At MindLab, we believe every discovery begins with what came before.

Our work builds upon decades of neuroscience, pharmacology, and human experience — merging known mechanisms into something entirely new: a therapy strong enough to match morphine, yet intelligent enough to control its consequences.
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Redefining Pain Medicine

For too long, the public conversation has blurred the line between addiction and drug abuse.

Most patients who suffer pain are not addicted; they were failed by drug designs that produced rapid reward spikes and by systems that enabled misuse.

While opioid use disorder (OUD) is real and devastating, much preventable harm arises from abuse and misuse – non-medical use, dose escalation, and diversion – often driven by reward (euphoria/drug liking) and excess exposure.
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MindLab’s mission is to lead a new era of pain therapeutics

One where pharmacology, formulation, and ethics work together to reduce abuse preventable harm (including abuse and misuse) without denying relief to those in need.

Our values underscore who we are:

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Empathy
Science begins
with listening
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Innovation
Transform what exists
into what’s needed
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Integrity
Evidence before
opinion
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Accountability
To patients, to partners,
to truth
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We are not avoiding morphine.
We are evolving it.

The Team

Leadership Team

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Larry Raoul James, JD, MBA
Founder & CEO
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Marco Pappagallo, MD
Chief Medical Officer, Designee
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Alexander Shtilbans, MD, PhD
Medical Director, Clinical Development, Designee
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Jeffrey J. Bettinger, PharmD
Director of Medical Affairs, Designee
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Team member
Andrew Hinton, JD
General Counsel & Chief Compliance Officer

Advisors

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David Heal, PhD, DSc, FRSC, FBPhS
Scientific Advisor
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Nathaniel Katz, MD, MS
Scientific Advisor
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Team member
Michael McFadden, BBA
Strategic Advisor

Mindlab collaborates with
world-class partners

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GNQ Insilico

GNQ Insilico is a TechBio company transforming drug development through a genomics driven platform that combines AI, systems biology, and quantum computing to build human digital twins and run in silico clinical trials.

GNQ collaborates with IBM and Deloitte to co develop and co market its digital twin and quantum enabled assessment platform, leveraging advanced AI and quantum infrastructure to simulate safety, efficacy, and dosing across diverse virtual patient populations.
GNQ scientists have co authored peer reviewed work on quantum optimized clinical trial design, and the company’s platform has been highlighted on major newswires for virtually simulating drug effects in thousands of synthetic patients with promising concordance to real world outcomes. MindLab is one of GNQ’s flagship pharma clients, using GNQ’s multi pathway digital twin modeling to independently validate and de risk MLB 001’s efficacy, safety window, and abuse liability profile before large scale clinical trials.

Learn More

MindLab is looking for partners and Investors. Join Us!

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